Discoveries in Cardiovascular Health and Disease
Western University, Schulich School of Medicine & Dentistry, Medical Sciences Building, 2nd Floor, London, ON, Canada
Oral Presentations in room M282; Poster sessions in room DSB 2005
July 4 – 6, 2024
Click here for a downloadable version.
Organizers: Tianqing Peng, Zhuxu Zhang and Qingping Feng (Western University)
Organizing Committee Members: Tianqing Peng, Zhuxu Zhang and Qingping Feng (Western University), Ren-Ke Li and Burton Yang (University of Toronto), Dake Qi (University of Manitoba), Guangdong Yang (Laurentian University), Dawei Zhang (University of Alberta), Ying Wang and Hong-Lin Luo (University of British Columbia), Xi-Long Zheng (University of Calgary), Wenbin Liang (University of Ottawa)
Preliminary Meeting Program
Thursday, July 4, 2024
Conference Registration Opens
Friday, July 5, 2024
8:20 – 9:00 AM Conference Registration
9:00 – 9:10 AM Opening remarks, Tianqing Peng, Zhuxu Zhang and Qingping Feng
9:10 – 9:15 AM Remarks from Rob Bartha, Vice Dean of Research, Schulich School of Medicine and Dentistry, Western University (to be confirmed)
9:15 – 9:20 AM Remarks from President of ACRE, Xuejun Wang, University of South Dakota
SESSION I. Cardiovascular Injury and Protection
Chairs: Wenbin Liang and Dawei Zhang
9:20 – 9:40 AM Cardiac toxicity of Bruton’s tyrosine kinase (BTK) inhibitors. Anargyros Xenocostas. Associate Professor of Medicine, Hematologist, London Health Sciences Centre, Western University, London, ON
9:40 – 10:00 AM Stat3 signaling in conditioning cardioprotection in normal and functionally impaired heart. Zhengyuan Xia, Associate Professor, University of Hong Kong, Hong Kong, China
10:00 – 10:20 AM The novel role of protease-activated receptor 2 (PAR2) in mediating myocardial ischemia-reperfusion injury. Dake Qi, Associate Professor of Pharmacy, University of Manitoba, Winnipeg, MB
10:20 – 10:40 AM Salt-Inducible Kinase 3: A Friend or Foe in Atherosclerotic Disease? Xi-Long Zheng, Professor of Biochemistry and Molecular Biology, Libin Cardiovascular Institute, University of Calgary, Calgary, AB
10:40 – 10:55 PM Refreshment Break and poster viewing (D2005)
SESSION II. Molecular Insights in Cardiovascular Disease
Chairs: Dake Qi and Xi-Long Zheng
10:55 – 11:15 AM Vascular regenerative cell deficiencies in South Asians with T2D: A story of diversity in Canadian health care. David Hess, Professor of Physiology and Pharmacology, Scientist at Robarts Research Institute, Western University, London, ON
11:15 – 11:35 AM Molecular mechanism of maintaining low-density lipoprotein cholesterol homeostasis and its therapeutic implications. Dawei Zhang, Professor of Pediatrics, University of Alberta, Edmonton, AB
11:35 – 11:55 AM TBA. Don Welsh, Professor of Physiology and Pharmacology, Scientist at Robarts Research Institute, Western University, London, ON
11:55 – 12:15 PM Identifying novel mechanosensitive receptors by custom high-throughput mechanical stimulation systems. Jie Xu, Professor, Sun Yat-sen University, Guangzhou, China
12:15 – 12:35 PM IPSC modeling for cardiovascular disease. Mark Chandy, Assistant Professor, Robarts Research Institute, Western University, London, ON
12:35 – 2:25 PM Box Lunch and trainee poster presentation (D2005)
SESSION III. ACRE International
Chairs: Ren-Ke Li and Tianqing Peng
2:25 – 2:45 PM Cardiac Pathophysiology of Proteasome Activation by PKA. Xuejun Wang, Professor and Director of the MD/PhD Program, University of South Dakota, Vermillion, SD, USA
2:45 – 3:05 PM Viperin mediates acute heart failure by activating SGK1 signaling. Hui Zheng, Professor, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China
3:05 – 3:25 PM Discovery of therapeutic targets for cardiovascular diseases. Lily Fuli Xiang, Associate Professor, Sun Yat-sen University, Guangzhou, China
3:25 – 3:45 PM Advancing causal gene discoveries to innovative targets for CVD. Eugene Chen, Professor, Pharmacology, Molecular and Integrative Physiology, and Internal Medicine, University of Michigan, Ann Arbor, MI, USA
3:45 – 4:00 PM Refreshment Break and poster viewing (D2005)
SESSION IV. Keynote Presentation
Chair: Qingping Feng and Ren-Ke Li
4:00 – 4:45 PM Keynote Presentation: Deconstructing vascular smooth muscle neighbourhoods. Dr. Geoffrey Pickering, Professor and Neil McKenzie Chair in Cardiac Care, Robarts Research Institute, Western University, London, ON, Canada
4:45 –5:00 PM Conference Photo
5:30 – 8:30 PM Conference Dinner for registered attendees
Saturday, July 6, 2024
SESSION V. Trainee Presentations
Chairs: Burton Yang and Guangdong Yang
9:00 – 9:15 AM TBA. PDF (Ying Wang’s lab), University of British Columbia
9:15 – 9:30 AM Viral subversion of autophagy: Insights into the pathogenic mechanisms of myocarditis. Yasir Mohamud, CIHR REDI career transition awardee, PDF of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC
9:30 – 9:45 AM
9:45 – 10:00 AM
10:00 –10:15 AM
10:15 – 10:30 AM
10:30 – 10:45 AM Refreshment Break and poster viewing (D2005)
SESSION VI. Novel Mechanisms and Cardiovascular Translation
Chairs: Zhuxu Zhang and Ying Wang
10:45 – 11:05 AM Regulation of cardiac ion channels by Wnt signalling. Wenbin Liang, Associate Professor of Cellular and Molecular Medicine, University of Ottawa Heart Institute, Ottawa, ON
11:05 – 11:25 AM H2S signaling and muscle health. Guangdong Yang (Laurentian University)
11:25 – 11:45 AM The role of mitochondrial DNA variation in cardiovascular disease risk. Christina Castellani, Assistant Professor of Pathology and Laboratory Medicine, Western University, London, ON
11:45 – 12:05 AM Cardiac fibrosis regulated by circular RNA encoded proteins. Burton Yang, Professor of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON
12:05 – 12:15 PM Trainee Poster Award presentation (Winner group photo)
12:15 – 12:20 PM Closing remarks, Ren-Ke Li
Lunch
1:00 – 3:00 PM ACRE Canada Business Meeting
The ACRE Canada Scientific Meeting Committee gratefully acknowledges the generous support of our event partners:
