New Frontiers in Atherosclerosis and Cardiovascular Diseases

Apotex Centre, Room 050

750 McDermot Avenue, Winnipeg, Manitoba, Canada

July 7-9, 2025

 

Gary Lopaschuk Memorial Lecture

 

Dr. Gary Lopaschuk was a Professor in Pediatrics and Pharmacology, and Scientific Director of Mazankowski Alberta Heart Institute at the University of Alberta. A Fellow of Royal Society of Canada and a global leader in cardiac metabolism, Dr. Lopaschuk had graciously agreed to deliver a keynote lecture at this conference before his passing. In his memory and in recognition of his pioneering contributions to cardiovascular research, the Gary Lopaschuk Memorial Lecture has been established and will be delivered by Dr. John Ussher, Professor of Pharmacy and Pharmaceutical Sciences, University of Alberta and a leading expert in pharmacotherapy of energy metabolism.

 

Keynote Speakers

 

Dr. Yu Huang is Jeanie Hu Professor of Biomedical Sciences, Chair professor of Biomedical Sciences and Vascular Biology and head of the Department of Biomedical Sciences at the City University of Hong Kong. His research focuses on understanding the cellular and molecular mechanisms underlying endothelial dysfunction associated with hypertension, obesity and diabetes. He is an internationally renowned leader in cardiovascular research and has published over 500 papers in prestigious journals including Nature and Science.

 

 

Dr. Lorrie Kirshenbaum is a professor in the Department of Pharmacology and Therapeutics, Max Rady College of Medicine at the University of Manitoba, Canada Research Chair in Molecular Cardiology, and Director of the Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre. Renowned globally for his expertise, Dr. Kirshenbaum is a leading authority in the study of cell death and autophagy and their roles in heart disease.

 

Click here for Registration and Abstract Submission

 

Conference Co-Chairs: Dr. Dake Qi (Pharmacy) and Dr. Garry Shen (Medicine), University of Manitoba

Local organizers: Dr. Jiming Kong (Anatomy and Cell Biology), Dr. Michael Czubryt (Physiology and Pathophysiology), and Dr. Sanjiv Dhingra (Physiology and Pathophysiology), University of Manitoba

Organizing Committee Members: Tianqing Peng and Qingping Feng (Western University), Burton Yang (U of Toronto), Dake Qi and Garry Shen (U of Manitoba), Guangdong Yang (Laurentian U), Dawei Zhang (U of Alberta), Ying Wang and Hong-Lin Luo (UBC), Xi-Long Zheng (U of Calgary), Wenbin Liang (U of Ottawa), Bernardo Trigatti (McMaster U).

Conference Program

Monday, July 7, 2025

 

7:30 – 9:00 AM                      Conference Registration, and Poster Setup (3rd floor hallway)

9:00 – 9:12 AM                       Opening Remarks (Rm. 050)

Dr. Dake Qi, University of Manitoba

Dr. Bernardo Trigatti, President of CSATVB, McMaster University

Dr. Qingping Feng, President of ACRE Canada, Western University

9:12 – 9:20 AM                       Dr. Hope Anderson, Dean and Professor, College of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba

Dr. Jude Uzonna, Vice Dean of Research, Rady Faculty of Health Sciences, University of Manitoba

 

SESSION I: Cell functions and heart disease

Co-Chairs: Bernardo Trigatti and Dake Qi

9:20 – 9:40 PM                       Wnt signaling and cardiac remodeling: ion channels and beyond

Dr. Wenbin Liang, University of Ottawa, Ottawa, ON, Canada

9:40 – 10:00 PM                     Multiplex imaging of human coronary lesions defines the phenotype of macrophages with impaired phagocytic activity

Dr. Ying Wang, University of British Columbia, Vancouver, BC, Canada

10:00 – 10:20 PM                  BRD4 in vascular aging: Understanding the epigenetic control of smooth muscle function

Dr. Xi-Long Zheng, University of Calgary, Calgary, AB, Canada

10:20 – 10:40 PM                  Unraveling the mechanism of myocarditis: Viral manipulation of autophagy

Dr. Honglin Luo, University of British Columbia, Vancouver, BC, Canada

 

10:40 – 11:10 AM                 Refreshment Break and Trainee Poster Presentation (3rd floor)

 

SESSION II: Development, Cardiac Injury and Regeneration

Co-Chairs: Wenbin Liang and Inna Rabinovich-Nikitin

11:10 – 11:30 AM                   Maternal environment in embryonic heart development: Role of eNOS

Dr. Qingping Feng, Western University, ON, Canada

11:30 – 11:50 AM                   Cardiac stem cell therapy: Still a long road to go

Dr. Sanjiv Dhingra, University of Manitoba, Winnipeg, MB, Canada

11:50 – 12:10 PM                   HDL and cell death in cardiovascular disease 

Dr. Bernardo Trigatti, McMaster University, Hamilton, ON, Canada

12:10 – 12:30 PM                   Type-dependent differences in cardiovascular remodeling under mechanical overload: A comparative study

Dr. Jian Wu, Zhongshan Hospital, Fudan University, Shanghai, China

 

12:30 – 2:00 PM                     Box lunch and trainee poster presentation (3rd floor)

 

SESSION III: Trainee Oral Presentations

Co-Chairs: Dawei Zhang and Ying Wang

2:00 – 2:15 PM                       Targeting Cardiac Necroptotic Cell Death in Diabetic Cardiomyopathy with Murine Cytomegalovirus M45. Sahanah Thirukumar, MSc candidate, Western University, London, ON, Canada

2:15 – 2:30 PM                       Circadian Disruption Exacerbates Heart Failure with Preserved Ejection Fraction. Ruzzell Flores, MSc candidate, University of Manitoba, Winnipeg, MB, Canada

2:30 – 2:45 PM                       Gestational Diabetes Mellitus Induced Cardiac Hypertrophy and Altered Mitochondrial Protein Acetylation in the Offspring Heart and the Protective Role of SIRT3. Caitlin Menzies, PhD candidate, University of Manitoba, Winnipeg, MB, Canada

2:45 – 3:00 PM                       Delivery of the gene encoding the N-terminus of murine cytomegalovirus M45 prevents PANoptosis and alleviates organ injury in septic mice. Chao Wang, PhD candidate, Western University, London, ON, Canada

3:00 – 3:15 PM                       Metabolic Dysfunction Attenuates D-dopachrome Tautomerase (DDT) Expression in the Heart – A Key Mechanism Exacerbates Myocardial Post-ischemic Injury. Lisha Li, PhD candidate, University of Manitoba, Winnipeg, MB, Canada

 

3:15 – 4:00 PM                     Refreshment Break and Trainee Poster Presentation (3rd floor)

 

SESSION IV: Keynote Presentation I

Chair: Dr. Qingping Feng

4:00 – 4:40 PM                      Circadian dependent regulation of cellular quality control mechanisms in the heart

Keynote Speaker: Dr. Lorrie Kirshenbaum, University of Manitoba, Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechsen Research Centre, Winnipeg, MB, Canada

 

4:40 – 4:50 PM                       Conference Group Photo

6:00 PM                                   Dinner on your own

6:00 – 7:30 PM                      CSATVB and CAS member meeting, Room 800 JBRC (by invitation only)

 

Tuesday, July 8, 2025

 

SESSION V: Keynote Presentation II

Chair: Dr. Garry Shen

9:00 – 9:40 PM                       Shear stress and vascular inflammation

Keynote Speaker: Dr. Yu Huang, City University of Hong Kong, Hong Kong, China

 

SESSION VI: Trainee Oral Presentations

Co-Chairs: Guangdong Yang and Sanjiv Dhingra

9:40 – 9:55 AM                       STIM1 C49S or C56S mutation dysregulates Ca²⁺ in atrial myocytes and increases susceptibility to atrial. Yanwen Li, PhD candidate, Western University, London, ON, Canada

9:55 – 10:10 AM                     MXene quantum dots for maturation of induced pluripotent stem cells derived cardiomyocytes. Keshav Narayan Alagarsamy, PhD candidate, University of Manitoba, Winnipeg, MB, Canada

10:10 – 10:25 AM                   Oxidized SOD1 is a causal factor in cellular senescence and biological aging. Dr. Teng Guan, PDF, University of Manitoba, Winnipeg, MB, Canada

10:25 – 10:40 AM                  Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα and inhibiting TGF-β1 and FHL1 signaling pathways. Dr. Yaning Shi, PDF, Hunan University of Chinese Medicine, Changsha, China

 

10:40 – 11:10 AM                   Refreshment Break and Trainee Poster Presentation (3rd floor)

 

SESSION VII: Smooth muscle and vascular diseases

Co-Chairs: Samantha Pauls and Heyu Ni

11:10 – 11:30 AM                   H₂S regulation of iron homeostasis in smooth muscle cells

Dr. Guangdong Yang, Laurentian University, Sudbury, ON, Canada

11:30 – 11:50 AM                   Interplay of scleraxis and AngII regulates vascular smooth muscle phenotype and blood vessel structure

Dr. Michael Czubryt, University of Manitoba, Winnipeg, MB, Canada

11:50 – 12:10 PM                  Activation of endothelial Nrf2 prevents atherosclerosis in ApoE-/- mice by inhibiting inflammation and lipid peroxidation

Dr. Cheng-Lin Zhang, Shenzhen University Medical School, Shenzhen, China

12:10 – 12:30 PM                   Using PAR2 pathway-biased agonists to target specific endothelium-dependent vascular smooth muscle relaxation mechanisms in mouse arteries

Dr. John McGuire, Western University, London, ON, Canada

 

12:30 – 2:00 PM                     Box Lunch and Trainee Poster Presentation (3rd floor)

 

SESSION VIII: Inflammation and metabolism

Co-Chairs: Michael Czubryt and Xi-Long Zheng

2:00 – 2:20 PM                       Impact of high nutrient loads and omega-3 fatty acids on monocyte metabolism and function

Dr. Samantha Pauls, University of Manitoba, Winnipeg, MB, Canada

2:20 – 2:40 PM                       HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis

Dr. Jinwei Tian, Harbin Medical University, 2^nd Affiliated Hospital, Harbin, China

2:40 – 3:00 PM                       Heart under stress: The impact of gestational diabetes on mitochondrial protein acetylation

Dr. Vernon Dolinsky, University of Manitoba, Winnipeg, MB, Canada

3:00 – 3:20 PM                       Gut hormones in the regulation of intestinal lipids

Dr. Changting Xiao, University of Saskatchewan, SK, Canada

 

3:20 – 4:00 PM                       Refreshment Break and Trainee Poster Presentation (3rd floor)

 

SESSION IX: Potential therapeutic strategies for cardiac diseases

Co-Chairs: Honglin Luo and Burton Yang

4:00 – 4:20 PM                       The influence of Saskatoon berry intake on metabolism and vascular function in healthy humans: relationship with gut microbiota and short chain fatty acids

Dr. Garry Shen, University of Manitoba, Winnipeg, MB, Canada

4:20 – 4:40 PM                       STAT3 signaling in conditioning cardioprotection in normal and functionally impaired heart

Dr. Zhengyuan Xia, University of Hong Kong, Hong Kong, China

4:40 – 5:00 PM                       Immunoengineered Smart MXene Nanosystems for Mitigation of Alloantigen Presentation and Prevention of Transplant Vasculopathy through Immunosuppressive Mechanisms

Dr. Alireza Rafieerad,  University of Manitoba, Winnipeg, MB, Canada

5:00 – 5:20 PM                     Strategies for rebalancing hematopoiesis against myocardial infarction and heart failure

Dr. Yaozu Xiang, Tongji University, Shanghai, China (virtual)

 

6:00 – 9:00 PM                       Conference dinner

 

Wednesday, July 9, 2025

 

SESSION X: Gary Lopaschuk Memorial Lecture

Chair: Vernon Delinsky

9:00 – 9:50 AM                      The Regulation of Cardiac Fatty Acid Metabolism via Malonyl CoA in Health and Disease: A Tribute to Dr. Gary Lopaschuk 

Dr. John Ussher, University of Alberta, Edmonton, Canada

9:50 – 10:30 AM                 Refreshments break and Trainee Poster Presentation (3rd floor)

 

SESSION XI: Potential therapeutic strategies for vascular diseases

Co-Chairs: Changting Xiao and Zhengyuan Xia

10:30 – 10:50 AM                   Control of Heart Attack and Stroke – developing novel anti-platelet therapy against atherothrombosis

Dr. Heyu Ni, University of Toronto, ON, Canada

10:50 – 11:10 AM                   Anti-atherosclerotic effect and mechanism of Tripterygium wilfordii

Dr. Li Qin, Hunan University of Traditional Medicine, Changsha, China

11:10 – 11:30 AM                   Vascular protection in atherosclerosis: unveiling the potential of traditional Chinese medicine

Dr. Guanwei Fan, Tianjin University of Traditional Chinese Medicine, Tianjin, China

11:30 – 11:50 AM                   A novel protein NAB1-356 encoded by circRNA circNAB1 regulates cardiac remodeling and fibrosis.

Dr. Burton Yang, University of Toronto, Toronto, ON, Canada

 

11:50 – 12:00 PM                   Trainee Presentation Award Ceremony

Group Photo of Awardees

12:00 – 12:10 PM                   Closing Remarks

Dr. Gary Shen, Conference Co-Chair, University of Manitoba

Dr. Wenbin Liang, Co-chair, Finance Committee, ACRE Canada

12:10 PM                                 Conference ends

12:10 – 2:00 PM                    ACRE Canada business meeting (Rm. 050)

 

Abstract / Poster Numbers:                                                   Click here for Abstract Book (coming soon)

MSc students

1. Farnoosh Tabatabaeian, Rita Wang, Kundanika Mukherjee, Ethan Minier, Changting Xiao. GLP-1R/GIPR Dual Agonism on Gut Lipid Handling. University of Saskatchewan, Saskatoon, SK, Canada.
2. Linhan Wang, Meng Mao, Hailong Bing, Wangli Tian, Xuan Wang, Wei Xu, Zhengyuan Xia, and Qinjun Chu. Post-Myocardial Infarction May cause Cognitive Dysfunction in mice through UDP-Glucose/P2Y14-Mediated Neuroinflammation. Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China.
3. Yuzhi Huang, Chuling Zhang, Ronghui Han, Linhan Wang, Zhengyuan Xia.  Normal Diet Reversion Mitigates Myocardial Damage in Mice with High-Fat-Diet and Streptozotocin-Induced Type 2 Diabetes. Affiliated Hospital of Guangdong Medical University, Guangdong, China.
4. Boaz Li, Samuel Leung, Gaea Buenaventura (presenting author), Maria Elishaev, Wan Hei Cheng, Giuseppe Mocci, Johan L M Björkegren, Chi Lai, Amrit Singh, Ying Wang. Spatial Gene Expression of Human Coronary Arteries Revealed the Molecular Features of Diffuse Intimal Thickening in Explanted Hearts. Centre for Heart Lung Innovation, University of British Columbia, Vancouver, BC, Canada
5. Thirukumar S, Ni R, Zhang J, Peng T. Targeting Cardiac Necroptotic Cell Death in Diabetic Cardiomyopathy with Murine Cytomegalovirus M45. London Health Sciences Centre Research Institute, Western University, London, ON, Canada.
6. Ruzzell Flores, Huong Nguyen, Inna Rabinovich-Nikitin. Circadian Disruption Exacerbates Heart Failure with Preserved Ejection Fraction. Institute of Cardiovascular Sciences, University of Manitoba, Winnipeg, MB, Canada.

PhD students

7. Caitlin Menzies, Mateuz Tomczyk, Bo Xiang, Stephanie Kereliuk, Richard Leduc, Vernon Dolinsky. Gestational Diabetes Mellitus Induced Cardiac Hypertrophy and Altered Mitochondrial Protein Acetylation in the Offspring Heart and the Protective Role of SIRT3. Children’s Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada.
8. Chao Wang, Rui Ni, Hu Xu, Guo-Chang Fan, Zhaoliang Su, Tianqing Peng. Delivery of the gene encoding the N-terminus of murine cytomegalovirus M45 prevents PANoptosis and alleviates organ injury in septic mice. London Health Sciences Centre Research Institute, Western University, London, ON, Canada.
9. Shiqi Huang, Peter Zahradka, Carla G. Taylor. The Endothelial Cell Response to Docosahexaenoic Acid is Growth State-Dependent: An RNA-seq Study. Canadian Centre for Agri-Food Research in Health and Medicine, University of Manitoba, Winnipeg, MB, Canada.
10. Yong-Fen Qi, Rui Wang (presenting author), Deng-Ren Ji. Intermedin inhibits DNA damage-mediated vascular aging by activating NAMPT/PARP1. Peking University Health Science Center, Beijing, China.
11. Lisha Li, Yadan Qi, Lin Leng, Hong Wu, Richard Bucala, Lawrence H Young, Dake Qi. Metabolic Dysfunction Attenuates D-dopachrome Tautomerase (DDT) Expression in the Heart – A Key Mechanism Exacerbates Myocardial Post-ischemic Injury. Rady Faculty of Health Science, University of Manitoba, Winnipeg, MB, Canada.
12. Yanwen Li, Sharon Lu, Peter Stathopulos, Qingping Feng. STIM1 C49S or C56S mutation dysregulates Ca²⁺ in atrial myocytes and increases susceptibility to atrial. Western University, London, ON, Canada.
13. Sikta Chattopadhyaya; Kimberley O’Hara; Teri Moffatt; Raghu Sundaresan Nagalingam; D. Allison Milosevic; Michael P. Czubryt.Impact of losartan on Angiotensin II-induced cardiac fibrosis and role of scleraxis in this pathway. Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, MB, Canada
14. Khushali Trivedi, Bo Xiang, Jewel Paskaruk, Ayesha Saleem& Vernon Dolinsky. SIRT3 Deficiency in the Liver is Associated with Hepatic Steatosis and Mitochondrial Dysfunction in Gestational Diabetes. Children’s Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada.
15. Zhihan Wang, Honglin Luo. Unraveling the Genetic Factors Influencing Susceptibility and Resistance to Viral Myocarditis. Heart Lung Innovation Center, University of British Columbia, Vancouver, BC, Canada.
16. Huili Li, Fei Xiao, Dake Qi, Huadong Zhu, Sheng Wang. Association between different insulin resistance surrogates and all-cause mortality in patients with cardiovascular disease: NHANES longitudinal cohort study. Peking Union Medical College Hospital, Beijing, China, University of Manitoba, Winnipeg, MB, Canada.
17. Hannah Zhang, Aleksandra Stamenkovic, Craig Resch, Ashish Shah, Amir Ravandi.Lysophospholipids as Markers of Cardiogenic Shock in STEMI Patients. Institute of Cardiovascular Sciences, St. Boniface Research Centre, University of Manitoba, Winnipeg, MB, Canada.
18. Keshav Narayan Alagarsamy, Leena Regi Saleth, Emily Hamm, Abhay Srivastava, Sanjiv Dhingra. MXene quantum dots for maturation of induced pluripotent stem cells derived cardiomyocytes. Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, MB, Canada.
19. Leena Regi Saleth, Alireza Rafieerad, Weiang Yan, Keshav N. Alagarsamy, Abhay Srivastava, Niketa Sareen, Sanjiv Dhingra. Immunomodulatory Ti₃C₂Tₓ Nanosheets for the Treatment and Prevention of Cardiac Allograft Vasculopathy. Institute of Cardiovascular Sciences, Albrechtsen St. Boniface Research Centre, University of Manitoba, Winnipeg, MB, Canada.
20. Besher M. Abual’anaz, Sara Haji Rasul, Sunil G. Rattan, Petra C. Kienesberger and Ian M. Dixon.  Sex Differences in Cardiac Fibromodulin Expression in Periostin Knockout (KO) Mice Exposed to Myocardial Infarction (MI). Institute of Cardiovascular Sciences, Albrechtsen Research Center, University of Manitoba, Winnipeg, Canada.

Postdocs/Research Associates

21. Qi Liu, Meggie Vo, Xiaoyun Ji, Morgan Black, Dongmei Sun, Elena Tsvetkova, Tianqing Peng. Tumor cell-derived SerpinA3 protects cardiomyocytes against doxorubicin-induced injury. London Health Sciences Centre Research Institute, Western University, London, ON, Canada.
22. Teng Guan, Ying Guo and Jiming Kong. Oxidized SOD1 is a causal factor in cellular senescence and biological aging. University of Manitoba, Winnipeg, MB, Canada.
23. Yaning Shi, Li Qin. Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα signaling pathway and inhibiting TGF-b1 and FHL1 signaling pathways. Hunan University of Chinese Medicine, Changsha, Hunan, China.
24. Amirhossein Bahreyni and Honglin Luo. Extracellular Vesicles as Key Players in Immune Cell Activation and Cardiac Remodeling in Viral Myocarditis. Heart Lung Innovation Center, University of British Columbia, Vancouver, BC, Canada
25. Abhay Srivastava, Glen Lester Sequiera, Niketa Sareen, Weiang Yan, Keshav Narayan Alagarsamy, Elika Verma, Cheryl Rockman-Greenberg, Sanjiv Dhingra. Development of iPSC-based clinical trial selection platform for patients with inherited metabolic and cardiovascular disorders. Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, MB, Canada.
26. Allen C. T. Teng, Jonathan St. Germain, Ava Vandenbelt, Shirony Nicholson, Shane Harding, Uros Kuzmanov, Brian Raught, Anthony O. Gramolini. Proteomic Analysis of Protein Aggresomes Reveals ARMC6 as a Stress-Induced Marker of Extrachromosomal DNA in Cells. Ted Rogers Centre for Heart Research, University Health Network, University of Toronto, Toronto, ON, Canada.
27. Alireza Rafieerad, Weiang Yan, Keshav N. Alagarsamy, Leena Regi Saleth, Abhay Srivastava, Niketa Sareen, Rakesh C. Arora, Sanjiv Dhingra. Immunoengineered Smart MXene Nanosystems for Mitigation of Alloantigen Presentation and Prevention of Transplant Vasculopathy through Immunosuppressive Mechanisms. Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, MB, Canada.

Faculty members

28. Guangdong Yang.  H₂S regulation of iron homeostasis in smooth muscle cells. School of Natural Sciences, Laurentian University, Sudbury, ON, Canada.
29. Cheng-Lin ZHANG, Lei HE, Qing-Hua CHEN, Yu HUANG. Activation of endothelial Nrf2 prevents atherosclerosis in ApoE^-/- mice by inhibiting inflammation and lipid peroxidation. Shenzhen University Medical School, Shenzhen, China; City University of Hong Kong, Hong Kong, China.
30. Chuanrui Ma, Yunqing Hua, Shu Yang, Guanwei Fan. Wogonin Attenuates Atherosclerosis via KLF11-Mediated Suppression of PPARα-YAP1-Driven Glycolysis and Enhancement of ABCA1/G1-Mediated Cholesterol Efflux. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
31. Gang Fan, Weiming Guo, Qingping Zhang, Jing Yang, Miao Liu.Potent Efficacy of Computer-Aided Designed Peptide Degrader Drug on PCSK9-Mediated Hypercholesterolemia. The 6th Affiliated Hospital of Shenzhen University, Shenzhen Nanshan Hospital, Shenzhen, China.
32. Honglin Luo. Unraveling the mechanism of myocarditis: Viral manipulation of autophagy. Heart Lung Innovation Center, University of British Columbia, Vancouver, BC, Canada.
33. William W Du, Hui Yuan, Muhammad Rafiq, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren-Ke Li, Huiming Guo, Burton B Yang. A novel protein NAB1-356 encoded by circRNA circNAB1 regulates cardiac remodeling and fibrosis. Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
34. Guanwei Fan and Chuanrui Ma. GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
35. Vernon Dolinsky. Heart under stress: The impact of gestational diabetes on mitochondrial protein acetylation. University of Manitoba, Winnipeg, MB, Canada.
36. Bernardo Trigatti. HDL and cell death in cardiovascular disease. McMaster University, Hamilton, ON, Canada.

The Conference Organizing Committee gratefully acknowledges the generous support of our event partners: